Journals Library

HTA - 07/16/01

Vitamin K to prevent fractures in older women: systematic review and economic evaluation

Project title: Vitamin K to prevent fractures in older women: systematic review and economic evaluation

Call to action: 07/16 Vitamin K to prevent fractures in older women

Research type: Evidence Synthesis

Chief investigator: Professor Matt StevensonORCID logo

Lead Author: Professor Matt StevensonORCID logo

Contractor: The University of Sheffield

Started: January 2008 | Status: Published October 2009

Study found that there is currently great uncertainty over whether vitamin K<sub>1</sub> is more cost-effective than alendronate in preventing osteoporotic fractures in postmenopausal women. Expected value of sample information analyses indicate that a head-to-head randomised controlled trial of alendronate and vitamin K<sub>1</sub>, recruiting 2000 women per arm, would be a cost-effective use of resources

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Background & Research Questions

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