Journals Library


HTA - 07/01/34

A randomised controlled trial to investigate the clinical and cost effectiveness of adding an ablation device-based maze procedure as a routine adjunct to elective cardiac surgery for patients with pre-existing atrial fibrillation (AMAZE)

Project title: A randomised controlled trial to investigate the clinical and cost effectiveness of adding an ablation device-based maze procedure as a routine adjunct to elective cardiac surgery for patients with pre-existing atrial fibrillation (AMAZE)

Call to action: 07/01 HTA Clinical Trials - June 2007 Board Submissions

Research type: Primary Research

Chief investigator: Mr Samer NashefORCID logo

Lead Author: Professor Linda SharplesORCID logo

Contractor: Papworth Hospital NHS Foundation Trust

Cost: £791,632.00

Co-investigators: Dr Alistair Grant, Dr Hester GoddardORCID logo, Dr Simon FynnORCID logo, Mr Matthew Dyer, Ms Pam Blomiley, Professor Linda SharplesORCID logo, Professor Martin Buxton.

Started: September 2008 | Status: Published April 2018

ISRCTN: 82731440

Adjunct atrial fibrillation surgery increased sinus rhythm restoration, cost about £3000 more, but did not improve quality-adjusted survival at 2 years.

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