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HTA - 06/403/51
A randomised controlled trial to compare the safety and effectiveness of doxycycline (200 mg/day) with prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid
Project title: A randomised controlled trial to compare the safety and effectiveness of doxycycline (200 mg/day) with prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid
Call to action: 06/403 HTA Clinical Trials - Pharmaceutical Panel - September 2006
Research type: Primary Research
Lead Author: Dr Joanne Chalmers
Contractor: The University of Nottingham
Started: October 2008 | Status: Published March 2017
The study found that a strategy of starting bullous pemphigoid patients on doxycycline is non-inferior to standard treatment with oral prednisolone for short-term blister control and considerably safer in the long term.
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