Journals Library


HTA - 06/303/20

CRASH2 Trial, a large randomised placebo controlled trial among trauma patients with significant haemorrhage of the effects of an antifibrinolytic treatment on death and transfusion requirement

Project title: CRASH2 Trial, a large randomised placebo controlled trial among trauma patients with significant haemorrhage of the effects of an antifibrinolytic treatment on death and transfusion requirement

Call to action: 06/303 HTA Clinical Trials - Pharmaceutical Panel

Research type: Primary Research

Chief investigator: Professor Ian Roberts

Lead Author: Professor Ian Roberts

Contractor: London School of Hygiene & Tropical Medicine

Cost: £2,545,661.00

Co-investigators: Dr Haleema Shakur, Professor Beverley Hunt, Professor Timothy Coats.

Started: April 2007 | Status: Published March 2013

ISRCTN: 86750102

Study found that early administration of tranexamic acid safely reduced the risk of death in bleeding trauma patients and is highly cost-effective.

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Background & Research Questions

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Methods

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Results

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