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Rachael Gooberman-Hill 1,2,*, Vikki Wylde 1,2, Wendy Bertram 3, Andrew J Moore 1, Rafael Pinedo-Villanueva 4, Emily Sanderson 5,6, Jane Dennis 1, Shaun Harris 5,6, Andrew Judge 1, Sian Noble 5,6, Andrew D Beswick 1, Amanda Burston 1, Tim J Peters 5, Julie Bruce 7, Christopher Eccleston 8, Stewart Long 9, David Walsh 10, Nicholas Howells 3, Simon White 11, Andrew Price 4, Nigel Arden 4, Andrew Toms 12, Candida McCabe 13, Ashley W Blom 1,2

1 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
2 UK National Institute for Health and Care Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK
3 Research and Innovation, North Bristol NHS Trust, Bristol, UK
4 Trauma and Orthopaedics, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, , UK
5 Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
6 Bristol Trials Centre, Bristol Randomised Trials Collaboration, University of Bristol, , UK
7 Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK
8 Centre for Pain Research, Department for Health, University of Bath, Bath, UK
9 Versus Arthritis, Chesterfield, UK
10 Pain Centre, Versus Arthritis, Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham, UK
11 Cardiff and Vale Orthopaedic Centre, Cardiff and Vale University Health Board, Cardiff, UK
12 Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter NHS Trust, Exeter, UK
13 Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK
* Corresponding author Email: r.gooberman-hill@bristol.ac.uk

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