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This study confirmed the results of the TOPKAT study and unicompartmental knee replacement was safer and less expensive than total knee replacement for patients with severe comorbidity.
1 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Nuffield Orthopaedic Centre, University of Oxford, Oxford, UK
2 Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Southmead Hospital, Bristol, UK
3 Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, Botnar Research Centre, Nuffield Orthopaedic Centre, University of Oxford, Oxford, UK
4 Medical Research Council Lifecourse Epidemiological Unit, University of Southampton, Southampton, UK
5 Department of Primary Care and Population Health, University College London, London, UK
6 Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
7 Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK
8 Research Committee, National Joint Registry for England, Wales, Northern Ireland and the Isle of Man, Hemel Hempstead, UK
9 College of Medicine and Health, University of Exeter, Exeter, UK
10 University of Exeter Medical School, Institute of Health Research, College of Medicine and Health, Exeter, UK
* Corresponding author Email: Victoria.strauss@csm.ox.ac.uk
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