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In children attending hospital with community-acquired pneumonia, antibiotic retreatment and adverse events were non-inferior for higher versus lower amoxicillin dose and 3-day versus 7-day treatment.

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Sam Barratt 1, Julia A Bielicki 2, David Dunn 1, Saul N Faust 3, Adam Finn 4, Lynda Harper 1,, Pauline Jackson 5, Mark D Lyttle 5,6, Colin VE Powell 7,8, Louise Rogers 9, Damian Roland 10,11, Wolfgang Stöhr 1, Kate Sturgeon 1, Elia Vitale 2, Mandy Wan 12, Diana M Gibb 1, Mike Sharland 2,*

1 MRC Clinical Trials Unit, University College London, London, UK
2 Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St George’s University of London, London, UK
3 NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University of Southampton, University Hospital Southampton NHS Foundation Trust, Southampton, UK
4 Bristol Children’s Vaccine Centre, School of Population Health Sciences/School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK
5 Emergency Department, Bristol Royal Hospital for Children, Bristol, UK
6 Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK
7 Paediatric Emergency Medicine Department, Sidra Medicine, Doha, The State of Qatar
8 School of Medicine, Cardiff University, Cardiff, UK
9 Research and Development Nursing Team, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK
10 Paediatric Emergency Medicine Leicester Academic (PEMLA) Group, University Hospitals of Leicester NHS Trust, Leicester, UK
11 SAPPHIRE Group, Health Sciences, Leicester University, Leicester, UK
12 Evelina Pharmacy, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
* Corresponding author Email:

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