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This study developed a prognostic model, including quantitative fetal fibronectin and clinical risk factors, that showed excellent performance in predicting spontaneous preterm birth within 7 days.

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Sarah J Stock 1,*, Margaret Horne 1, Merel Bruijn 1, Helen White 2, Robert Heggie 3, Lisa Wotherspoon 4, Kathleen Boyd 3, Lorna Aucott 5, Rachel K Morris 6, Jon Dorling 7, Lesley Jackson 8, Manju Chandiramani 9, Anna David 10, Asma Khalil 11, Andrew Shennan 12, Gert-Jan van Baaren 13, Victoria Hodgetts-Morton 5, Tina Lavender 2, Ewoud Schuit 14, Susan Harper-Clarke 15, Ben Mol 16, Richard D Riley 17, Jane Norman 4, John Norrie 1

1 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK
2 Division of Nursing, Midwifery and Social Work, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
3 Health Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
4 Medical Research Council Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
5 Health Services Research Unit, University of Aberdeen, Aberdeen, UK
6 Institute of Applied Health Research, University of Birmingham, Birmingham, UK
7 Department of Neonatology, IWK Health Centre, Halifax, NS, Canada
8 Department of Neonatology, Queen Elizabeth Hospital, Glasgow, UK
9 Department of Obstetrics and Gynaecology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
10 Elizabeth Garrett Anderson Institute for Women’s Health, University College London, London, UK
11 Department of Fetal Medicine, St George’s Hospital, St George’s, University of London, London, UK
12 Department of Women and Children’s Health, School of Life Course Sciences, King’s College London, London, UK
13 Department of Obstetrics and Gynaecology, Amsterdam University Medical Center, Amsterdam, the Netherlands
14 Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands
15 Public and patient representative, Teddington, UK
16 Department of Obstetrics and Gynaecology, Monash University, Melbourne, VIC, Australia
17 Centre for Prognosis Research, Research Institute for Primary Care and Health Sciences, Keele University, Keele, UK
* Corresponding author Email:

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