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This study suggested that a multicentre trial comparing the effectiveness of broad-spectrum antibiotics and active observation to appendicectomy is feasible.
1 Faculty of Medicine, University of Southampton, Southampton, UK
2 Department of Health Services Research, Institute of Population Health Sciences, University of Liverpool, Liverpool, UK
3 University College London Great Ormond Street Institute of Child Health, Department of Population Health Sciences, University College London, London, UK
4 Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
5 Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
6 Southampton Health Technology Assessment Centre, Faculty of Medicine, University of Southampton, Southampton, UK
7 Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, UK
8 National Institute for Health Research (NIHR), Research Design Service South Central, University of Southampton, Southampton, UK
9 Department of Paediatric Surgery and Urology, Southampton Children’s Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, UK
10 Department of Paediatric Surgery, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
11 Department of Paediatric Surgery, St George’s University Hospitals NHS Foundation Trust, London, UK
12 Southampton Clinical Trials Unit, University of Southampton, Southampton, UK
13 Patient and public involvement representative, ,
14 Centre for Surgical Research, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
* Corresponding author Email: n.j.hall@soton.ac.uk
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