Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis

Armstrong, Nigel; Büyükkaramikli, Nasuh; Penton, Hannah; Riemsma, Rob; Wetzelaer, Pim; Huertas Carrera, Vanesa; Swift, Stephanie; Drachen, Thea; Raatz, Heike; Ryder, Steve; Shah, Dhwani; Buksnys, Titas; Worthy, Gill; Duffy, Steven; Al, Maiwenn; Kleijnen, Jos

doi:10.3310/hta24510

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The addition of avatrombopag or lusutrombopag was superior to usual clinical care in avoiding platelet transfusion, but the benefits were modest and with a high cost per QALY.

Nigel Armstrong , Nasuh Büyükkaramikli , Hannah Penton , Rob Riemsma , Pim Wetzelaer , Vanesa Huertas Carrera , Stephanie Swift , Thea Drachen , Heike Raatz , Steve Ryder , Dhwani Shah , Titas Buksnys , Gill Worthy , Steven Duffy , Maiwenn Al & Jos Kleijnen .

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Nigel Armstrong ^1,^*, Nasuh Büyükkaramikli ², Hannah Penton ², Rob Riemsma ¹, Pim Wetzelaer ², Vanesa Huertas Carrera ¹, Stephanie Swift ¹, Thea Drachen ¹, Heike Raatz ¹, Steve Ryder ¹, Dhwani Shah ¹, Titas Buksnys ¹, Gill Worthy ¹, Steven Duffy ¹, Maiwenn Al ², Jos Kleijnen ¹

¹ Kleijnen Systematic Reviews, York, UK
² Erasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, the Netherlands
^* Corresponding author Email: nigel@systematic-reviews.com

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