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The active device did not reduce the frequency of severe asthma exacerbations more than the placebo.

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Melissa Kapoor 1, Will Storrar 2, Lara Balls 2, Thomas P Brown 2, Adel Mansur 3, Emma Hedley 4, Tom Jones 2, Claire Roberts 2, Beverly Shirkey 5, Susan Dutton 5, Ramon Luengo-Fernandez 6, Matthew Little 6, Ann Dewey 7, Sue Marshall 2, Carole Fogg 2,7Table 6, Keith Boughton 2, Najib Rahman 4, Ly-Mee Yu 8, Peter Bradding 9, Peter Howarth 10, Anoop J Chauhan 2,7,*

1 South East Health Technologies Alliance, Henfield, UK
2 Portsmouth Hospitals NHS Trust, Respiratory Department, Portsmouth, UK
3 Heartlands Hospital, Respiratory Department, Birmingham, UK
4 Oxford Respiratory Trials Unit, University of Oxford, Oxford, UK
5 Oxford Clinical Trials Research Unit, Centre for Statistics in Medicine, University of Oxford, Oxford, UK
6 Health Economics Research Centre, University of Oxford, Oxford, UK
7 School of Health Sciences and Social Work, University of Portsmouth, Portsmouth, UK
8 Primary Care Trials Unit, Nuffield Department of Primary Care Health, University of Oxford, Oxford, UK
9 Leicester Respiratory Biomedical Research Unit, Leicester, UK
10 University Hospital Southampton NHS Foundation Trust, Respiratory Department, Southampton, UK
* Corresponding author Email:

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