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Nine months of CBT for clozapine-resistant schizophrenia did not improve the primary outcome of total symptoms at 21 months, although symptoms seemed to be improved at end of treatment.

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Anthony P Morrison 1,2,*,, Melissa Pyle 1,2,, Andrew Gumley 3, Matthias Schwannauer 4, Douglas Turkington 5, Graeme MacLennan 6, John Norrie 7, Jemma Hudson 6, Samantha Bowe 1, Paul French 1,8, Paul Hutton 9, Rory Byrne 1,2, Suzy Syrett 3, Robert Dudley 10, Hamish J McLeod 3, Helen Griffiths 4, Thomas RE Barnes 11, Linda Davies 12, Gemma Shields 12, Deborah Buck 12, Sarah Tully 1,2, David Kingdon 13

1 Psychosis Research Unit, Greater Manchester Mental Health NHS Foundation Trust, Prestwich, UK
2 Division of Psychology and Mental Health, University of Manchester, Manchester, UK
3 Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
4 Department of Clinical Psychology, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK
5 Academic Psychiatry, Northumberland, Tyne and Wear NHS Foundation Trust, Centre for Ageing and Vitality, Newcastle General Hospital, Newcastle upon Tyne, UK
6 Centre for Healthcare Randomised Trials, Health Services Research Unit, University of Aberdeen, Aberdeen, UK
7 Clinical Trials Unit, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK
8 Institute of Psychology, Health and Society, University of Liverpool, Liverpool, UK
9 School of Health and Social Care, Edinburgh Napier University, Edinburgh, UK
10 School of Psychology, Newcastle University, Newcastle upon Tyne, UK
11 Centre for Mental Health, Imperial College London, London, UK
12 Division of Population Health, University of Manchester, Manchester, UK
13 Department of Psychiatry, University of Southampton, Academic Centre, Southampton, UK
* Corresponding author Email:

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