Aerobic and strength training exercise programme for cognitive impairment in people with mild to moderate dementia: the DAPA RCT

Lamb, Sarah E; Mistry, Dipesh; Alleyne, Sharisse; Atherton, Nicky; Brown, Deborah; Copsey, Bethan; Dosanjh, Sukhdeep; Finnegan, Susanne; Fordham, Beth; Griffiths, Frances; Hennings, Susie; Khan, Iftekhar; Khan, Kamran; Lall, Ranjit; Lyle, Samantha; Nichols, Vivien; Petrou, Stavros; Zeh, Peter; Sheehan, Bart

doi:10.3310/hta22280

An error occurred retrieving publication content to display, please try again.

Page not found (404)

Sorry - the page you requested could not be found.

Please choose a page from the navigation or try a website search above to find the information you need.

Extended Research Article

Toolkit

View Award

A structured exercise programme, while well tolerated and enjoyed, did not produce any clinically meaningful benefit in cognitive function for people with dementia, and a slight worsening was observed.

Sarah E Lamb , Dipesh Mistry , Sharisse Alleyne , Nicky Atherton , Deborah Brown , Bethan Copsey , Sukhdeep Dosanjh , Susanne Finnegan , Beth Fordham , Frances Griffiths , Susie Hennings , Iftekhar Khan , Kamran Khan , Ranjit Lall , Samantha Lyle , Vivien Nichols , Stavros Petrou , Peter Zeh & Bart Sheehan .

Detailed Author information
Detailed Author information

Sarah E Lamb ^1,^2,^3,^*, Dipesh Mistry ², Sharisse Alleyne ², Nicky Atherton ², Deborah Brown ³, Bethan Copsey ^1,³, Sukhdeep Dosanjh ², Susanne Finnegan ², Beth Fordham ³, Frances Griffiths ², Susie Hennings ², Iftekhar Khan ², Kamran Khan ², Ranjit Lall ², Samantha Lyle ³, Vivien Nichols ², Stavros Petrou ², Peter Zeh ², Bart Sheehan ⁴

¹ Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
² Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK
³ Centre for Rehabilitation Research In Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
⁴ Oxford University Hospitals NHS Foundation Trust, Oxford, UK
^* Corresponding author Email: sarah.lamb@ndorms.ox.ac.uk

Funding: {{metadata.Funding}}

{{metadata.Journal}} Volume: {{metadata.Volume}}, Issue: {{metadata.Issue}}, Published in {{metadata.PublicationDate | date:'MMMM yyyy'}}

https://doi.org/{{metadata.DOI}}

Citation:{{author}}{{ (($index < metadata.AuthorsArray.length-1) && ($index <=6)) ? ', ' : '' }}{{(metadata.AuthorsArray.length <= 6) ? '.' : '' }} {{(metadata.AuthorsArray.length > 6) ? 'et al. ' : ''}}. {{metadata.JournalShortName}} {{metadata.PublicationDate | date:'yyyy'}};{{metadata.Volume}}({{metadata.Issue}})

Report Content

Full Report
Abstract
Plain English Summary
Plain Language Summary
Scientific Summary

The full text of this issue is available as a PDF document from the Toolkit section on this page.

Responses to this report

No responses have been published.

If you would like to submit a response to this publication, please do so using the form below:

Comments submitted to the NIHR Journals Library are electronic letters to the editor. They enable our readers to debate issues raised in research reports published in the Journals Library. We aim to post within 14 working days all responses that contribute substantially to the topic investigated, as determined by the Editors. Non-relevant comments will be deleted.

Your name and affiliations will be published with your comment.

Once published, you will not have the right to remove or edit your response. The Editors may add, remove, or edit comments at their absolute discretion.

Enter response message*

Name (title, first name, last name)*

Occupation / Job title*

Affiliation / Employer*

Email*

Other authors
For example, if you are responding as a team or group. Please ensure you include full names and separate these using commas

Statement of competing interests
We believe that readers should be aware of any competing interests (conflicts of interest).
The International Committee of Medical Journal Editors (ICMJE) define competing interests as including: financial relationships with industry (for example through employment, consultancies, stock, ownership, honoraria, and expert testimony), either directly or through immediate family; personal relationships; academic competition; and intellectual passion.

If yes, please provide details below

Enter response title*

Enter CAPTCHA What is six multiplied by three?*

By submitting your response, you are stating that you agree to the terms & conditions

An error has occurred in processing the XML document