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There is some limited evidence for the clinical and cost-effectiveness of second-line treatments for axillary hyperhidrosis and a RCT of botulinum toxin versus iontophoresis for palmar hyperhidrosis may be warranted.

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Ros Wade, Stephen Rice, Alexis Llewellyn, Eoin Moloney, Julie Jones-Diette, Julija Stoniute, Kath Wright, Alison M Layton, Nick J Levell, Gerard Stansby, Dawn Craig & Nerys Woolacott.

Ros Wade 1, Stephen Rice 2, Alexis Llewellyn 1, Eoin Moloney 2, Julie Jones-Diette 1, Julija Stoniute 2, Kath Wright 1, Alison M Layton 3, Nick J Levell 4, Gerard Stansby 5, Dawn Craig 2, Nerys Woolacott 1,*

1 Centre for Reviews and Dissemination, University of York, York, UK
2 Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK
3 Harrogate and District NHS Foundation Trust, Harrogate, UK
4 Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK
5 The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
* Corresponding author Email:

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