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Nicholas James 1,2,*, Sarah Pirrie 3, Ann Pope 3, Darren Barton 3, Lazaros Andronis 4, Ilias Goranitis 4, Stuart Collins 3, Duncan McLaren 5, Joe O’Sullivan 6, Chris Parker 7, Emilio Porfiri 1, John Staffurth 8,9, Andrew Stanley 10, James Wylie 11, Sharon Beesley 12, Alison Birtle 13, Janet Brown 14, Prabir Chakraborti 15, Martin Russell 16, Lucinda Billingham 3

1 Department of Oncology, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK
2 Cancer Research Unit, University of Warwick, Coventry, UK
3 Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, UK
4 Health Economics Unit, University of Birmingham, Birmingham, UK
5 Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK
6 Department of Oncology, Belfast City Hospital, Belfast, UK
7 Department of Oncology, Royal Marsden Hospital, Sutton, UK
8 Institute of Cancer and Genetics, Cardiff University, Cardiff, UK
9 Velindre Cancer Centre, Cardiff, UK
10 Pharmacy Department, City Hospital, Birmingham, UK
11 Department of Oncology, The Christie Hospital, Manchester, UK
12 Kent Oncology Centre, Maidstone Hospital, Kent, UK
13 Rosemere Cancer Centre, Royal Preston Hospital, Preston, UK
14 Department of Oncology, St James’ University Hospital, Leeds, UK
15 Department of Oncology, Royal Derby Hospital, Derby, UK
16 Beatson West of Scotland Cancer Centre, Glasgow, UK
* Corresponding author Email: nicholas.james@uhb.nhs.uk

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