A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN)

Chakravarthy, Usha; Harding, Simon P; Rogers, Chris A; Downes, Susan; Lotery, Andrew J; Dakin, Helen A; Culliford, Lucy; Scott, Lauren J; Nash, Rachel L; Taylor, Jodi; Muldrew, Alyson; Sahni, Jayashree; Wordsworth, Sarah; Raftery, James; Peto, Tunde; Reeves, Barnaby C; ,

doi:10.3310/hta19780

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A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN)

Usha Chakravarthy, Simon P Harding, Chris A Rogers, Susan Downes, Andrew J Lotery, Helen A Dakin, Lucy Culliford, Lauren J Scott, Rachel L Nash, Jodi Taylor, Alyson Muldrew, Jayashree Sahni, Sarah Wordsworth, James Raftery, Tunde Peto, Barnaby C Reeves & .

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Usha Chakravarthy ^1,^*, Simon P Harding ², Chris A Rogers ³, Susan Downes ⁴, Andrew J Lotery ⁵, Helen A Dakin ⁶, Lucy Culliford ³, Lauren J Scott ³, Rachel L Nash ³, Jodi Taylor ³, Alyson Muldrew ¹, Jayashree Sahni ², Sarah Wordsworth ⁶, James Raftery ⁷, Tunde Peto ⁸, Barnaby C Reeves ³, ^†

¹ Centre for Experimental Medicine, Institute of Clinical Science, Queen’s University Belfast, Belfast, UK
² Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK
³ Clinical Trials and Evaluation Unit, School of Clinical Sciences, University of Bristol, Bristol, UK
⁴ Oxford University Hospitals NHS Trust, Oxford, UK
⁵ Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
⁶ Health Economic Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
⁷ Wessex Institute, University of Southampton, Southampton, UK
⁸ National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK
^* Corresponding author Email: u.chakravarthy@qub.ac.uk^† Corresponding author Email:

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