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Study found insufficient evidence to support definite clinical recommendations regarding vitamin D supplementation in pregnancy. Although there is modest evidence to support a relationship between maternal 25-hydroxy vitamin D [25(OH)D] status and offspring birthweight, bone mass and serum calcium concentrations, these findings were limited by their observational nature (birthweight, bone mass) or risk of bias and low quality (calcium concentrations).

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Nicholas C Harvey,1,2,*,† Christopher Holroyd,1,† Georgia Ntani,1 Kassim Javaid,3 Philip Cooper,1 Rebecca Moon,1 Zoe Cole,1 Tannaze Tinati,1 Keith Godfrey,1,2 Elaine Dennison,1 Nicholas J Bishop,4 Janis Baird,1,2 Cyrus Cooper,1,2,3 

1 Medical Research Council (MRC) Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK
2 National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK
3 National Institute for Health Research (NIHR) Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK
4 Academic Unit of Child Health, Department of Human Metabolism, University of Sheffield, Sheffield, UK
* Corresponding author ; Email:

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https://dx.doi.org/{{metadata.DOI}}

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