The value of FDG positron emission tomography/ computerised tomography (PET/CT) in pre-operative staging of colorectal cancer: a systematic review and economic evaluation

Brush, J; Boyd, K; Chappell, F; Crawford, F; Dozier, M; Fenwick, E; Glanville, J; McIntosh, H; Renehan, A; Weller, D; Dunlop, M

doi:10.3310/hta15350

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Study found insufficient evidence to support the routine use of FDG PET-CT in primary colorectal cancer and only a small amount of evidence supporting its use in the pre-operative staging of recurrent and metastatic colorectal cancer. Economic evaluation showed that FDG PET/CT as an add-on imaging device is cost-effective in the pre-operative staging of recurrent colon, recurrent rectal and metastatic disease but not primary colon or rectal cancers.

J Brush, K Boyd, F Chappell, F Crawford, M Dozier, E Fenwick, J Glanville, H McIntosh, A Renehan, D Weller & M Dunlop.

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J Brush ¹, K Boyd ², F Chappell ³, F Crawford ^4,^*, M Dozier ⁵, E Fenwick ², J Glanville ⁶, H McIntosh ⁴, A Renehan ⁷, D Weller ⁴, M Dunlop ⁸

¹ Department of Radiology, Western General Hospital, Edinburgh, UK
² Institute of Health and Wellbeing, The University of Glasgow, Glasgow, UK
³ Division of Clinical Neurosciences, The University of Edinburgh, Edinburgh, UK
⁴ The Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK
⁵ The Main Library, The University of Edinburgh, Edinburgh, UK
⁶ York Health Economics Consortium, Ltd, The University of York, York, UK
⁷ Department of Surgery, The Christie NHS Foundation Trust, The University of Manchester, Manchester, UK
⁸ School of Molecular and Clinical Medicine, The University of Edinburgh, Edinburgh, UK
^* Corresponding author Email: fay.crawford@ed.ac.uk

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