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Six days of daily low-dose prednisolone during an upper respiratory tract infection does not reduce associated relapse of steroid sensitive nephrotic syndrome in UK children.

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Martin T Christian 1,*,, Nicholas JA Webb 2,, Rebecca L Woolley 3, Nafsika Afentou 4, Samir Mehta 3, Emma Frew 4, Elizabeth A Brettell 3, Adam R Khan 3, David V Milford 5, Detlef Bockenhauer 6, Moin A Saleem 7, Angela S Hall 8, Ania Koziell 9, Heather Maxwell 10, Shivaram Hegde 11, Eric R Finlay 12, Rodney D Gilbert 13, Caroline Jones 14, Karl McKeever 15, Wendy Cook 16, Natalie Ives 3

1 Department of Paediatric Nephrology, Nottingham Children’s Hospital, Nottingham, UK
2 Department of Paediatric Nephrology, University of Manchester, Academic Health Science Centre, Royal Manchester Children’s Hospital, Manchester, UK
3 Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK
4 Health Economics Unit, University of Birmingham, Birmingham, UK
5 Department of Paediatric Nephrology, Birmingham Children’s Hospital, Birmingham, UK
6 Department of Renal Medicine, University College London, Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, London, UK
7 School of Clinical Sciences, University of Bristol, Department of Paediatric Nephrology, Bristol Royal Hospital for Children, Bristol, UK
8 Leicester Children’s Hospital, Leicester, UK
9 Child Health Clinical Academic Group, King’s College London, Department of Paediatric Nephrology, Evelina London Children’s Hospital, London, UK
10 Department of Paediatric Nephrology, Royal Hospital for Sick Children, Glasgow, UK
11 Department of Paediatric Nephrology, University Hospital of Wales, Cardiff, UK
12 Department of Paediatric Nephrology, Leeds Children’s Hospital, Leeds, UK
13 Department of Paediatric Nephrology, Southampton Children’s Hospital, Southampton, UK
14 Department of Paediatric Nephrology, Alder Hey Children’s Hospital, Liverpool, UK
15 Department of Paediatric Nephrology, Royal Hospital for Sick Children, Belfast, UK
16 Nephrotic Syndrome Trust (NeST), Taunton, UK
* Corresponding author Email: martin.christian@nuh.nhs.uk

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