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This trial only recruited 21% of its target due to lack of capacity, however, its novel qualitative findings and sham design can inform photobiomodulation researchers and service providers.

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Michael Nugent 1,*, Valerie Bryant 2, Chrissie Butcher 3, Holly Fisher 4, Sean Gill 3, Rebecca Goranova 5, Shaun Hiu 4, Lyndsay Lindley 6, James O’Hara 7, Yemi Oluboyede 4, Joanne Patterson 8, Tim Rapley 9, Tomos Robinson 4, Nikki Rousseau 4,10, Vicky Ryan 4, Ramkumar Shanmugasundaram 11, Linda Sharp 4, Ruby Smith Whelan 3, Deborah D Stocken 10, Laura Ternent 4, Janet Wilson 4, Jenn Walker 3

1 Department of Oral and Maxillofacial Surgery, City Hospitals Sunderland NHS Foundation Trust, Sunderland, UK
2 Change Head and Neck Cancer Research Patient Involvement Group, Sunderland, UK
3 Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK
4 Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK
5 Plymouth Oncology Centre, University Hospitals Plymouth NHS Trust, Plymouth, UK
6 Social Policy Research Unit, University of York, York, UK
7 Ear, Nose and Throat Department, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
8 School of Health Sciences, University of Liverpool, Liverpool, UK
9 Department of Social Work, Education and Community Wellbeing, Northumbria University, Newcastle upon Tyne, UK
10 Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK
11 Clinical Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK
* Corresponding author Email: Michaelnugent@nhs.net

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