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Hyaluronan-based sperm selection did not increase live birth rates for women receiving intracytoplasmic sperm injection-based assisted reproductive treatment.

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Jackson Kirkman-Brown 1,2, Sue Pavitt 3, Yacoub Khalaf 4, Sheena Lewis 5, Richard Hooper 6, Siladitya Bhattacharya 7, Arri Coomarasamy 2, Vinay Sharma 8, Daniel Brison 9, Gordon Forbes 6, Robert West 10, Allan Pacey 11, Kate Brian 12, Rachel Cutting 13, Virginia Bolton 14, David Miller 14,*

1 Birmingham Women’s Fertility Centre, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK
2 Institute of Metabolism and Systems Research, University of Birmingham, Birmingham Women’s Hospital, Birmingham, UK
3 Dental Translational and Clinical Research Unit (DenTCRU), Leeds National Institute for Health Research Clinical Research Facility, University of Leeds, Leeds, UK
4 Guy’s and St Thomas’ NHS Foundation Trust, London, UK
5 Examen Ltd, Belfast, UK
6 Pragmatic Clinical Trials Unit, Centre for Primary Care and Public Health, Queen Mary University of London, London, UK
7 College of Biomedical and Life Sciences, Cardiff University School of Medicine, Cardiff, , UK
8 Leeds Fertility, Leeds Teaching Hospitals NHS Trust, Seacroft Hospital, Leeds, UK
9 Department of Reproductive Medicine, Old St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK
10 Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
11 Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK
12 Fertility Network UK, London, UK
13 Sheffield Teaching Hospitals NHS Trust, Sheffield, UK
14 Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
* Corresponding author Email:

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