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Low-dose intradermal immunotherapy for seasonal allergic rhinitis had no clinical effect even though it suppressed skin late responses to allergen.

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Anna Slovick 1,2, Abdel Douiri 3, Rachel Muir 4, Andrea Guerra 1, Konstantinos Tsioulos 1, Evie Haye 1, Emily PS Lam 1, Joanna Kelly 5, Janet L Peacock 3, Sun Ying 1, Mohamed H Shamji 6, David J Cousins 1,2,7, Stephen R Durham 6, Stephen J Till 1,2,*

1 Division of Asthma, Allergy and Lung Biology, King’s College London, School of Medicine, Guy’s Hospital, London, UK
2 Medical Research Council (MRC)–Asthma UK, Centre for Allergic Mechanisms of Asthma, London, UK
3 Division of Health and Social Care Research, King’s College London, London, UK
4 Clinical Research Facility, NIHR Biomedical Research Centre, Guy’s Hospital, London, UK
5 King’s Clinical Trials Unit, King’s College London, Institute of Psychiatry, London, UK
6 Allergy and Clinical Immunology, National Heart and Lung Institute, Faculty of Medicine, Imperial College, London, UK
7 Department of Infection, Immunity and Inflammation, National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Research Unit, Leicester Institute for Lung Health, University of Leicester, Leicester, UK
* Corresponding author Email: stephen.till@kcl.ac.uk

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